Dr James Richardson

Dr James Richardson

Post-doctoral researcher (2009-2013)

James finished his PhD in the Brown group in 2009, his thesis entitled Novel DNA probes for sensitive DNA detection, then remained in the group as a post-doctoral researcher. His main areas of interest were novel genetic analysis methods and the use of DNA in nano-engineering applications, with an interest in fluorescently labelled DNA and detection methodologies. After leaving the Brown Group in 2013 James joined Illumina and now works as a Senior Scientist in the Systems Integration department in Cambridge, UK.

12 Papers

SERS-Melting: A New Method for Discriminating Mutations in DNA Sequences

S. Mahajan, J. A. Richardson, T. Brown and P. N. Bartlett. J. Am. Chem. Soc. 130 (46), 15589-15601, 2008.

The Use of an Electroactive Marker as a SERS Label in an E-melting Mutation Discrimination Assay

S. Mahajan, J. A. Richardson, N. Ben Gaied, Z. Y. Zhao, T. Brown and P. N. Bartlett. Electroanalysis 21 (20), 2190-2197, 2009.

End-capped HyBeacon probes for the analysis of human genetic polymorphisms related to warfarin metabolism

N. Ben Gaied, J. A. Richardson, D. G. Singleton, Z. Y. Zhao, D. French and T. Brown. Org. Biomol. Chem. 8 (12), 2728-2734, 2010.

Six-Colour HyBeacon Probes for Multiplex Genetic Analysis

J. A. Richardson, M. Gerowska, M. Shelbourne, D. J. French and T. Brown. ChemBioChem 11 (18), 2530-2533, 2010.

Gauging the Flexibility of Fluorescent Markers for the Interpretation of Fluorescence Resonance Energy Transfer

J. J. Rindermann, Y. Akhtman, J. A. Richardson, T. Brown and P. G. Lagoudakis. J. Am. Chem. Soc. 133 (2), 279-285, 2011.

Efficient reverse click labeling of azide oligonucleotides with multiple alkynyl Cy-Dyes applied to the synthesis of HyBeacon probes for genetic analysis

M. Gerowska, L. M. Hall, J. A. Richardson, M. Shelbourne and T. Brown. Tetrahedron 68 (3), 857-864, 2012.

Real-Time Surface-Enhanced Raman Spectroscopy Monitoring of Surface pH during Electrochemical Melting of Double-Stranded DNA

R. P. Johnson, J. A. Richardson, T. Brown and P. N. Bartlett. Langmuir 28 (12), 5464-5470, 2012.

A Label-Free, Electrochemical SERS Based Assay for the Detection of DNA Hybridization and the Discrimination of Mutations

R. P. Johnson, J. A. Richardson, T. Brown and P. N. Bartlett. J. Am. Chem. Soc. 134 (34), 14099-14107, 2012.

Denaturation of dsDNA Immobilised at a Negatively Charged Gold Electrode is not caused by Electrostatic Repulsion

R. P. Johnson, N. Gale, J. A. Richardson, T. Brown and P. N. Bartlett. Chem. Sci. 4, 1625-1632, 2013.

Use of a large Stokes-shift fluorophore to increase the multiplexing capacity of a point-of-care DNA diagnostic device

J. A. Richardson, T. Morgan, M. Andreou and T. Brown. Analyst 138, 3626-3628, 2013.

Rapid detection of diagnostic targets using isothermal amplification and HyBeacon probes – A homogenous system for sequence-specific detection

R. L. Howard, D. J. French, J. A. Richardson, C. E. O'Neill, M. P. Andreou, T. Brown, D. Clark, I. N. Clarke, J. W. Holloway, P. Marsh and P. G. Debenham. Mol. Cell. Probes 29 (2), 92-98, 2015.

Synthesis and use of universal sequence probes in fluorogenic multi-strand hybridisation complexes for economical nucleic acid testing

D. J. French, J. A. Richardson, R. L. Howard, T. Brown and P. G. Debenham. Mol. Cell. Probes 29 (4), 228-236, 2015.